FIGURE

Fig. S2

ID
ZDB-FIG-150810-16
Publication
Evason et al., 2015 - Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish
Other Figures
All Figure Page
Back to All Figure Page
Fig. S2

Zebrafish livers with activated β-catenin share histologic features with human hepatocellular carcinoma (HCC).

(A) Adult zebrafish livers with activated β-catenin (left) and human HCC (right) show architectural disruption including enlarged interhepatic spaces resembling spongiosis hepatis (zebrafish) or peliosis hepatis (human) (asterisks). (B-D) Similarly, zebrafish (left) and human (right) samples show cytological abnormalities including nuclear enlargement and nuclear contour irregularities (arrows, B), prominent nucleoli (arrows, C), and mitotic figures (arrows, D). Hematoxylin and eosin (H&E) stained sections; scale bars, 20 µm.
Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.