FIGURE

Fig. 5

ID

ZDB-FIG-140515-13

Publication

Toruno et al., 2014 - Interdependence of Bad and Puma during ionizing-radiation-induced apoptosis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

Bad radiosensitizes zebrafish neural tissue through the mitochondrial apoptosis pathway.

(A) Shown are lateral views of 27-hpf wild-type embryos (head is top left in each panel) injected with either 1) 50 pg of egfp mRNA, 2) 25 pg each of egfp and bad, 3) 25 pg each of egfp and zbcl-xL, or 4) 25 pg each of bad and zbcl-xL. At 24 hpf, half of each group was irradiated with 8 Gy IR and analyzed three hours later by the Casp3 assay. (B) Fluorescence intensity was measured in the spinal cords of at least 10 embryos from each group. Data represent one experiment, but the experiment was independently performed three times with similar results.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One