FIGURE

Fig. 7

ID

ZDB-FIG-130906-29

Publication

Sorrell et al., 2013 - Tcf7l1 proteins cell autonomously restrict cardiomyocyte and promote endothelial specification in zebrafish

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Fig. 7

The expression domains of etv2 and tal1 are truncated in Tcf7l1 deficient embryos. ((A)–(D)) Etv2 and ((E)–(H)) tal1 expression at the 8 s stage in control, Tcf7l1a, Tcf7l1b, and Tcf7l1 deficient embryos. Etv2 and tal1 expression are slightly more truncated in Tcf7l1a deficient embryos compared to Tcf7l1b deficient embryos. The effects on etv2 and tal1 expression at this stage in Tcf7l1 deficient embryos is equivalent to Tcf7l1a deficient embryos. Images are dorsal with anterior up. Arrows in (A)–(H) indicate distance between the anterior and posterior limits of expression.

Expression Data

Genes:	etsrp tal1
Fish:	WT WT + MO1-tcf7l1a + MO4-tp53 WT + MO1-tcf7l1b + MO4-tp53 WT + MO1-tcf7l1a + MO1-tcf7l1b + MO4-tp53
Knockdown Reagents:	MO1-tcf7l1a MO1-tcf7l1b MO4-tp53
Anatomical Term:	anterior lateral plate mesoderm
Stage:	5-9 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 380(2), Sorrell, M.R., Dohn, T.E., D'Aniello, E., and Waxman, J.S., Tcf7l1 proteins cell autonomously restrict cardiomyocyte and promote endothelial specification in zebrafish, 199-210, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.