FIGURE

Fig. 7

ID

ZDB-FIG-130710-1

Publication

Parrie et al., 2013 - Zebrafish tbx5 paralogs demonstrate independent essential requirements in cardiac and pectoral fin development

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Fig. 7

Loss of Tbx5a or Tbx5b differentially affects the expression of conserved mammalian Tbx5 target genes. mRNA levels for candidate target genes were quantified by qPCR. Data are represented as the mean ± S.E. Differences in expression, measured in log-transformed values of copy number per ug template RNA, were analyzed by ANOVA. A Tukey-Kramer post hoc test was used to determine statistical differences between samples (*P < 0.05, **P < 0.001). A,B: The zebrafish Tbx5 paralogs. C-F: Candidate direct targets of Tbx5 based on conservation among vertebrates. G: A house-keeping gene used as a standard control.

Expression Data

Genes:	bmp4 hey2 nppa tbx2b tbx5a tbx5b (all 6)
Fish:	WT tbx5a^m21/m21 WT + MO1-tbx5b
Knockdown Reagent:	MO1-tbx5b
Anatomical Term:	whole organism
Stage Range:	Prim-15 to Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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