ZFIN is now using GRCz12tu for Genomic Data
Gene
hey2
- ID
- ZDB-GENE-000526-1
- Name
- hes-related family bHLH transcription factor with YRPW motif 2
- Symbol
- hey2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within with a positive effect on cardiac muscle cell proliferation. Acts upstream of or within cardiac muscle tissue regeneration; circulatory system development; and negative regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in several structures, including alar plate midbrain region; cardiovascular system; hematopoietic system; mesoderm; and nervous system. Orthologous to human HEY2 (hes related family bHLH transcription factor with YRPW motif 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 76 figures from 62 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu521 (19 images)
Wild Type Expression Summary
- All Phenotype Data
- 17 figures from 10 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Hairy and Enhancer of Split/HEY-related | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain | Orange domain |
|---|---|---|---|---|---|---|
| UniProtKB:Q9I9L0 | InterPro | 324 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
- Genome Browsers