Fig. S4
- ID
- ZDB-FIG-130507-16
- Publication
- Choudhry et al., 2013 - DiGeorge Syndrome Gene tbx1 Functions through wnt11r to Regulate Heart Looping and Differentiation
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tbx1-/- embryos have defects in heart performance. (A) Measurement of ventricular contractility as shortening fraction [(width at diastole – width at systole)/width at diastole] shows no difference between WT and tbx1-/- embryos. (B) Determination of atrium contractility between WT and tbx1-/- embryos. The stroke volume (ventricular volume [diastole - systole]) plotted in C is unaffected in tbx1-/- embryos, but the heart rate is decreased, shown in D. N = 19 in all experiments. WT siblings are represented in green and tbx1-/- mutants in pink. p-values are reported under each measurement. |
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Stage Range: | Long-pec to Protruding-mouth |