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Fig. S4
tbx1-/- embryos have defects in heart performance. (A) Measurement of ventricular contractility as shortening fraction [(width at diastole – width at systole)/width at diastole] shows no difference between WT and tbx1-/- embryos. (B) Determination of atrium contractility between WT and tbx1-/- embryos. The stroke volume (ventricular volume [diastole - systole]) plotted in C is unaffected in tbx1-/- embryos, but the heart rate is decreased, shown in D. N = 19 in all experiments. WT siblings are represented in green and tbx1-/- mutants in pink. p-values are reported under each measurement.
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