FIGURE

Fig. S6

ID

ZDB-FIG-101108-10

Publication

Hellman et al., 2010 - The zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretch

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Fig. S6

efhc1, tektin-1, and dnahc9 expression in the pronephros is foxj1a and foxj1b dependent. In situ hybridization analysis in control, foxj1a morphant (MO), foxj1b MO, and foxj1a+b double morphants at 24 hpf demonstrated that combined foxj1a/b double knockdown uniformly abolished expression of cilia motility associated genes but not other kidney specific markers or foxj1a itself. (A-D) EF-hand containing domain 1 (efhc1), (E-H) tektin-1, (I-K) dynein heavy chain 9 (dnahc9), (M-P) pax2a, (Q-T) shippo, (U-X) foxj1a (n > 15 embryos for each condition). (A, E, I, M, Q, U) Control embryos; (B, F, J, N, R, V) foxj1a MO; (C, G, K, O, S, W) foxj1b MO; (D, H, L, P, T, X) combined foxj1a/b knockdown.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA