FIGURE

Fig. 8

ID

ZDB-FIG-080715-9

Publication

Mei et al., 2008 - C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis

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Fig. 8

C1q-like MO affects the hematopoiesis and brain blood vessel organization. (A) The embryo phenotypes stained by O-dianisidine at 48 hpf. The embryos are shown as lateral views (a, c, e) and ventral views. (B) The effect of C1q-like MO on brain (a, b, c) and tail (d, e, f) blood vessels in the flk-1:GFP-transgenic zebrafish. The blood vessels of embryos were imaged at 48 hpf at 10x. Arrows show the mesencephalic vein (MsV). Each picture represents typical results from three experiments (more than 20 embryos in each experiment).

Expression Data

Gene:	grcfp
Fish:	zf528Tg zf528Tg + MO1-c1ql4l zf528Tg + MO1-c1ql4l + MO4-tp53
Knockdown Reagents:	MO1-c1ql4l MO4-tp53
Anatomical Terms:	brain vasculature mesencephalic vein post-vent vasculature trunk vasculature
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-c1ql4l WT + MO1-c1ql4l + MO4-tp53 zf528Tg + MO1-c1ql4l zf528Tg + MO1-c1ql4l + MO4-tp53
Knockdown Reagents:	MO1-c1ql4l MO4-tp53
Observed In:	cranial vasculature mesencephalic vein nucleate erythrocyte hemoglobin complex post-vent vasculature trunk vasculature
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 319(2), Mei, J., Zhang, Q.Y., Li, Z., Lin, S., and Gui, J.F., C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis, 273-284, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.