FIGURE

Fig. 2

ID

ZDB-FIG-080411-64

Publication

Delalande et al., 2008 - Zebrafish sip1a and sip1b are essential for normal axial and neural patterning

Other Figures

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Fig. 2

Effect of sip1a and sip1b splice blocking antisense morpholino oligonucleotide injection on survival and morphological development at 24-72hpf. A: Bar graph showing the percent of surviving sip1a SBMO morphants, sip1b SBMO morphants, and sip1a sip1b double morphants at 24, 48, and 72 hpf. The numbers represent the percent of injected embryos surviving at each specific time point ± s.e.m. based on 3 independent experiments. B-M: Lateral views of control (B, F, J), sip1a morphant (C, G, K), sip1b morphant (D, H, L), and sip1a sip1b double morphant (E, I, M) embryos at 24hpf (B-E), 48hpf (F-I), and 72 (J-M) hpf. Anterior is to the left.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO2-zeb2a WT + MO2-zeb2b WT + MO2-zeb2a + MO2-zeb2b
Knockdown Reagents:	MO2-zeb2a MO2-zeb2b
Observed In:	brain central nervous system development convergent extension involved in axis elongation dorsal/ventral pattern formation heart post-anal tail morphogenesis whole organism anterior-posterior axis (all 7)
Stage Range:	Prim-5 to Protruding-mouth

Phenotype Detail

Acknowledgments

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