Fig. 8
- ID
- ZDB-FIG-071227-20
- Publication
- Esguerra et al., 2007 - Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination
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Double Ttrap and Smad3b knockdown rescues CE defect in Ttrap knockdown. myod marks paraxial/adaxial mesoderm (8 ss). (A) Broadened somites and a wide distance between myod cells in Ttrap single knockdown embryo. (B) A combination of 16 ng TtrapMO and 1 ng Smad3bMO shows closer convergence of myod cells at midline. However, somitic expression is still broad relative to the fully rescued embryo co-injected with 2 ng Smad3bMO (C), which now displays the normal myod domain. Dorsal views, anterior at top. |
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Stage: | 5-9 somites |