FIGURE

Fig. 5

ID
ZDB-FIG-070815-30
Publication
French et al., 2007 - Pbx homeodomain proteins pattern both the zebrafish retina and tectum
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Fig. 5

The expression of rx2, rx3, and atoh7 is aberrant in pbx2/4 null embryos. The expression of rx3, the earliest known eye field marker is unaffected at the tailbud and 4 somite stage (A-D) but is increased in expression at the 10 somite stage (H) when compared to wildtype (G). The expression of rx2 is reduced at both the 4 and 10 somite stage in pbx2/4 null embryos (F and J), when compared to wildtype (E and I). No expression of rx2 is observed at the tailbud stage. The expression of atoh7 was analyzed as a marker of differentiating retinal ganglion cells. In wild type embryos, expression begins in the ventral nasal domain of the retina at about 31 hpf (K). Expression proceeds in a wave-like fashion to include the dorsal retina by 36 hpf (L), and has filled the entire retina by 41 hpf (M). In pbx2/4 null embryos, expression is initiated correctly at 31 hpf (N). Expression proceeds in a wave-like fashion but is excluded from the dorsal domain of the retina at both 36 hpf (O) and 41 hpf (P).

Expression Data
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage Range: 1-4 somites to Prim-25

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage Range: 1-4 somites to Prim-25

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.