ZFIN Morpholino: MO1-hoxb1a

Target Location

Genome Build: GRCz11Chromosome: 3

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-hoxb1a

No data available

Phenotype

Phenotype resulting from MO1-hoxb1a

Phenotype	Fish	Figures
cell migration in hindbrain disrupted, abnormal	rw0Tg + MO1-hoxb1a	Fig. 5 from Hurley et al., 2007
facial nerve development disrupted, abnormal	rw0Tg + MO1-hoxb1a	Fig. 5 from Hurley et al., 2007
hindbrain neuron mislocalised, abnormal	rw0Tg + MO1-hoxb1a	Fig. 5 from Hurley et al., 2007
neuron migration disrupted, abnormal	rw0Tg + MO1-hoxb1a	Fig. 5 from Hurley et al., 2007
rhombomere 4 development disrupted, abnormal	WT + MO1-hoxb1a	Fig. 3 , Fig. 4 from Rohrschneider et al., 2007

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Phenotype of all Fish created by or utilizing MO1-hoxb1a

Phenotype	Fish	Conditions	Figures
rhombomere 4 development disrupted, abnormal	WT + MO1-hoxb1a	standard conditions	Fig. 3 , Fig. 4 from Rohrschneider et al., 2007
facial nerve development disrupted, abnormal	rw0Tg + MO1-hoxb1a	standard conditions	Fig. 5 from Hurley et al., 2007
neuron migration disrupted, abnormal	rw0Tg + MO1-hoxb1a	standard conditions	Fig. 5 from Hurley et al., 2007
cell migration in hindbrain disrupted, abnormal	rw0Tg + MO1-hoxb1a	standard conditions	Fig. 5 from Hurley et al., 2007
hindbrain neuron mislocalised, abnormal	rw0Tg + MO1-hoxb1a	standard conditions	Fig. 5 from Hurley et al., 2007

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Citations

Include unpublished citations

Beiriger, A., Narayan, S., Singh, N., Prince, V. (2020) Development and migration of the zebrafish rhombencephalic octavolateral efferent neurons. The Journal of comparative neurology. 529(7):1293-1307
Addison, M., Xu, Q., Cayuso, J., Wilkinson, D.G. (2018) Cell Identity Switching Regulated by Retinoic Acid Signaling Maintains Homogeneous Segments in the Hindbrain. Developmental Cell. 45:606-620.e3
Labalette, C., Wassef, M.A., Desmarquet-Trin Dinh, C., Bouchoucha, Y.X., Le Men, J., Charnay, P., Gilardi-Hebenstreit, P. (2015) Molecular dissection of segment formation in the developing hindbrain. Development (Cambridge, England). 142:185-95
Choe, S.K., Ladam, F., and Sagerström, C.G. (2014) TALE factors poise promoters for activation by Hox proteins. Developmental Cell. 28(2):203-211
Erickson, T., Pillay, L.M., and Waskiewicz, A.J. (2011) Zebrafish Tshz3b negatively regulates Hox function in the developing hindbrain. Genesis (New York, N.Y. : 2000). 49(9):725-42
Walsh, G.S., Grant, P.K., Morgan, J.A., and Moens, C.B. (2011) Planar polarity pathway and Nance-Horan syndrome-like 1b have essential cell-autonomous functions in neuronal migration. Development (Cambridge, England). 138(14):3033-3042
Stedman, A., Lecaudey, V., Havis, E., Anselme, I., Wassef, M., Gilardi-Hebenstreit, P., and Schneider-Maunoury, S. (2009) A functional interaction between Irx and Meis patterns the anterior hindbrain and activates krox20 expression in rhombomere 3. Developmental Biology. 327(2):566-577
French, C.R., Erickson, T., Callander, D., Berry, K.M., Koss, R., Hagey, D.W., Stout, J., Wuennenberg-Stapleton, K., Ngai, J., Moens, C.B., and Waskiewicz, A.J. (2007) Pbx homeodomain proteins pattern both the zebrafish retina and tectum. BMC Developmental Biology. 7(1):85
Hurley, I.A., Scemama, J.L., and Prince, V.E. (2007) Consequences of Hoxb1 duplication in teleost fish. Evolution & development. 9(6):540-554
Rohrschneider, M.R., Elsen, G.E., and Prince, V.E. (2007) Zebrafish Hoxb1a regulates multiple downstream genes including prickle1b. Developmental Biology. 309(2):358-372

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