Gene

xirp2a

ID

ZDB-GENE-040108-7

Name

xin actin binding repeat containing 2a

Symbol

xirp2a Nomenclature History

Previous Names

xirp2
sb:cb1045
wu:fc12g12
Xin beta6 (1)

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization. Predicted to act upstream of or within actin filament bundle assembly; heart development; and negative regulation of actin filament depolymerization. Predicted to be located in cell junction. Predicted to colocalize with focal adhesion and stress fiber. Is expressed in several structures, including fin; forebrain; musculature system; pericardial region; and somite. Orthologous to human XIRP2 (xin actin binding repeat containing 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

46 figures from 20 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb1045 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With xirp2a Human Ortholog

No data available

Associated With xirp2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001781	Zinc finger, LIM-type
Family	IPR028740	LIM domain and actin-binding protein 1
Family	IPR030072	Xin actin-binding repeat-containing protein 1/2
Family	IPR030107	Xin actin-binding repeat-containing protein 2
Family	IPR045268	LIM domain and actin-binding protein LIMA-like
Repeat	IPR012510	Actin-binding, Xin repeat

Domain Details Per Protein

Protein	Length	Actin-binding, Xin repeat	LIM domain and actin-binding protein 1	LIM domain and actin-binding protein LIMA-like	Xin actin-binding repeat-containing protein 1/2	Xin actin-binding repeat-containing protein 2	Zinc finger, LIM-type
UniProtKB:F8W4U4 InterPro	3315
UniProtKB:Q4V9G7 InterPro	263
UniProtKB:F8W3Z4 InterPro	807

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Length (nt)	Analysis
mRNA	xirp2a-201 (1) Ensembl	10784 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	xirp2a-202 (1) Ensembl	4032 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-xirp	polyclonal	xirp1 xirp2a		Rabbit	WB		1
Ab1-xirp2a	polyclonal	xirp2a		Rabbit			1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations