Gene

pard3ab

ID
ZDB-GENE-030925-47
Name
par-3 family cell polarity regulator alpha, b
Symbol
pard3ab Nomenclature History
Previous Names
  • ASIP (1)
  • asip
  • par-3
  • par3
  • pard3
  • bazooka
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Is predicted to enable phosphatidylinositol binding activity. Involved in several processes, including cell adhesion; establishment of cell polarity; and microtubule cytoskeleton organization. Acts upstream of or within several processes, including blood vessel development; eye development; and nervous system development. Located in apical plasma membrane; cell-cell junction; and cytoplasm. Is expressed in brain; neuroepithelial cell; and retina. Orthologous to human PARD3 (par-3 family cell polarity regulator).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
32 figures from 10 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pard3ab Human Ortholog
No data available
Associated With pard3ab Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001478 PDZ domain
Domain IPR021922 Par3/HAL, N-terminal
Homologous_superfamily IPR036034 PDZ superfamily
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab3-pard3 polyclonal Rabbit
  • IHC
1
Ab1-pard3 polyclonal Rabbit
  • IHC
  • WB
2
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations