Gene

thoc2

ID
ZDB-GENE-030616-54
Name
THO complex 2
Symbol
thoc2 Nomenclature History
Previous Names
  • Tho2 (1)
  • fb73e08
  • fd21d11
  • si:bz1o18.2
  • wu:fb73e08
  • wu:fd21d11
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to localize to THO complex part of transcription export complex. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human THOC2 (THO complex 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With thoc2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
X-linked intellectual disability-short stature-overweight syndrome Alliance Intellectual developmental disorder, X-linked 12 300957
Associated With thoc2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR021418 THO complex, subunitTHOC2, C-terminal
Domain IPR021726 THO complex, subunitTHOC2, N-terminal
Domain IPR032302 THO complex subunit 2, N-terminal domain
Family IPR040007 THO complex subunit 2
Domain Details Per Protein
Protein Length THO complex subunit 2 THO complex subunit 2, N-terminal domain THO complex, subunitTHOC2, C-terminal THO complex, subunitTHOC2, N-terminal
UniProtKB:F1R5B5 1535
UniProtKB:Q7ZZ88 1430
UniProtKB:A0A0R4IXB9 154
UniProtKB:Q6DRE1 1504
UniProtKB:F1QXF4 1560
UniProtKB:Q1JPZ4 920
UniProtKB:Q567N6 328
UniProtKB:F1RCI0 1504
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations