FIGURE

Fig 5

ID

ZDB-FIG-260710-14

Publication

Williams-Ward et al., 2026 - Yap1 regulates motility and vertebral development and prevents kyphoscoliosis in zebrafish

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Fig 5

Kyphoscoliosis arises in yap1^kg151 mutants from 13 days.
(A) Larval fish at 27 days deriving from a female yap1^kg151 x male yap1^kg151/+ cross reared at 20.5 ºC until 7 days (5 dpf-equivalent) and then at 26.5 ºC. Wholemount fish before (upper) and after (lower) skeletal stain for bone (red) and cartilage (blue). Note reduced dorsoventral extent in severely kyphoscoliotic mutant (right). (B,C) Several examples of larval fish deriving from a yap1^kg151/+ in-cross reared at 20.5 ºC until 7 days and then at 26.5 ºC stained live with calcein. Lateral views of 18 days (B) and 13 days (C). Numbers indicate fraction of fish of each genotype with morphology shown. Bars = 1 mm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	yap1^kg151/kg151
Observed In:	skeletal system
Stage Range:	Days 7-13 to Days 21-29

Phenotype Detail

Acknowledgments

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