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Varga et al., 2025 - Transposon insertion causes ctnnb2 transcript instability that results in the maternal effect zebrafish ichabod (ich) mutation

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Fig. 3

The position of EnSpm transposons observed in this study vary across zebrafish genomes. (A) Genomic positions of EnSpm-N49 (orange), EnSpm-N49B (pink) and EnSpm-N49/N49B (green) transposons in nonoverlapping 2-Mbp windows across the nuclear chromosomes of the Tübingen (Tue) GRCz11 reference genome. Inner circle shows the coverage of protein-coding genes on the same chromosomes. (B, C) Genomic positions of the observed transposons show variability across the genomes of multiple wild-type isolates for chromosomes 5 (B) and 6 (C). (Y axis denotes copy numbers in the 2-Mbp windows. Strain abbreviations can be found in Table 3. For other chromosomes see Supplementary Fig. 4.)

Expression Data

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Antibody Labeling

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Acknowledgments

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Reprinted from Biochimica et biophysica acta. Gene regulatory mechanisms, , Varga, Z., Kagan, F., Maegawa, S., Nagy, Á., Okendo, J., Burgess, S.M., Weinberg, E.S., Varga, M., Transposon insertion causes ctnnb2 transcript instability that results in the maternal effect zebrafish ichabod (ich) mutation, 195104195104, Copyright (2025) with permission from Elsevier. Full text @ BBA Gene Regulatory Mechanisms