FIGURE

Fig. 4 - Supplemental 2

ID

ZDB-FIG-250611-10

Publication

Qin et al., 2025 - Unraveling the role of Ctla-4 in intestinal immune homeostasis through a novel Zebrafish model of inflammatory bowel disease

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4 - Supplemental 2

Examination on the involvement of apoptotic process in epithelial cells and expression of inflammation-related genes in neutrophils and B cells in the intestines of ctla-4-/- zebrafish. (A) Expression map of the epithelial markers within the cell populations of the zebrafish intestines. (B) Expression map of the neutrophil markers within the cell populations of the zebrafish intestines. (C) KEGG enrichment bar plot of all differentially expressed genes (DEGs) from epithelial cells. (D) Quantification of TUNEL-positive cells per 1×104 μm2 in WT and ctla-4-/- posterior intestines (n=5). (E) Heatmap of inflammation-related genes in B cells from wild-type and ctla-4-/- intestines. Statistical significance was assessed through an unpaired Student’s t-test (***p < 0.001).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife