FIGURE
Fig. 6
- ID
- ZDB-FIG-250512-82
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- Li et al., 2025 - 2-Hydroxy-4-n-octyloxybenzophenone induces developmental neurotoxicity and multiple sclerosis-like symptoms through cacna1a regulated Ca2 + inward flow and microglial activation
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Fig. 6
Schematic representation of UV-531-induced developmental neurotoxicity and MS-like symptoms. Exposure to UV-531 induces a significant upregulation of cacna1a, leading to increased Ca2+ inflow, resulting in an imbalance in calcium homeostasis as well as neuronal damage. It also caused microglia activation, inducing an inflammatory environment that drove myelin injure. Thus, UV-531 induced developmental neurotoxicity and MS-like symptoms. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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