FIGURE

Figure 6

ID

ZDB-FIG-240620-204

Publication

Wei et al., 2024 - Ace Deficiency Induces Intestinal Inflammation in Zebrafish

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Figure 6

Inflammatory response evaluation for ace^−/− mutants and wild-type larvae at 5 dpf. (A,B) qRT-PCR analysis of selected inflammation-related genes. (C) AB-PAS staining sections label mucus in the intestine of both ace^−/− mutants and wild-type larvae at 5 dpf (upper panel). The lower panels provide enlarged photographs of the intestinal bulb and mid- and posterior intestine regions. The red arrowhead in the figure indicates the staining signal. (D) Cell statistics for Alcian blue staining in the digestive tract of ace^−/− mutants and wild-type larvae at 5 dpf. Data are presented as the mean ± SD of 10 fish. ** p < 0.01, *** p < 0.001. The experiments were independently repeated three times.

Expression Data

Genes:	cxcl8b.1 il1b lect2.1 mmp9 mmp13a.2 mmp14b mmp30 mpx (all 8)
Fish:	AB ace^{ouc1004/ouc1004} (AB)
Anatomical Term:	whole organism
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ace^{ouc1004/ouc1004} (AB)
Observed In:	intestine goblet cell intestine mucus layer whole organism
Stage:	Day 5

Phenotype Detail

Acknowledgments

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