FIGURE

Fig. 7

ID

ZDB-FIG-240208-16

Publication

Audira et al., 2023 - A comprehensive painkillers screening by assessing zebrafish behaviors after caudal fin amputation

Other Figures

All Figure Page

Back to All Figure Page

Fig. 7

Comparison of inflammatory, antioxidant activity, oxidative stress, and neurotransmitter biomarkers levels in zebrafish brain tissues measured using enzyme-linked immunosorbent assay (ELISA) among fin-amputated groups treated with five ppm of the painkillers, and the fin-amputated group treated with five ppm of DMSO (red color bar) and unamputated group (blue color bar) as the control groups at one-hour post-amputation. Twelve biomarkers were quantified, which were (A) COX-1, (B) COX-2, (C) IL-6, (D) ACh, (E) AChE, (F) ROS, (G) 5-HT, (H) cortisol, and (I) dopamine. Data are presented as mean with SEM and were analyzed by one-way ANOVA test followed with Tukey's multiple comparisons test (n = 6, except the combination group (n = 5)); ✱ p < 0.05, ✱✱ p < 0.01, ✱✱✱ p < 0.001, the red asterisk (top) indicates a statistical difference to the amputated group + DMSO, the blue asterisk (bottom) indicates a statistical difference to the unamputated group).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biomed. Pharmacother.