FIGURE

Fig. 3

ID

ZDB-FIG-231201-50

Publication

Li et al., 2023 - FK506-binding protein 5 regulates cell quiescence-proliferation decision in zebrafish epithelium

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Fig. 3

Fkbp5 promotes NaR cell quiescence-proliferation transition. (A, B) Effect of FK506. Tg(igfbp5a:GFP) embryos were raised in E3 medium to 3 dpf and transferred to the control and induction medium with or without 10 μm FK506. NaR cells were quantified at 5 dpf. Representative images were shown in (A) and quantified data in (B). Scale bar = 0.2 mm. Data shown are mean ± SD. n = 37~58. (C, D) Tg(igfbp5a:GFP) embryos were injected with Cas9 mRNA and gRNAs targeting fkbp5 (C), fkbp7 (D) or scrambled gRNA at the one-cell stage. They were raised in E3 solution to 3 dpf and transferred to the control (Control) or induction medium (induced). NaR cells were quantified 2 days later. Data shown are mean ± SD. n = 17 ~ 69.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ FEBS Lett.