ZFIN Image: Li et al., 2023, Fig. 3

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Figure Caption

Fig. 3 Fkbp5 promotes NaR cell quiescence-proliferation transition. (A, B) Effect of FK506. Tg(igfbp5a:GFP) embryos were raised in E3 medium to 3 dpf and transferred to the control and induction medium with or without 10 μm FK506. NaR cells were quantified at 5 dpf. Representative images were shown in (A) and quantified data in (B). Scale bar = 0.2 mm. Data shown are mean ± SD. n = 37~58. (C, D) Tg(igfbp5a:GFP) embryos were injected with Cas9 mRNA and gRNAs targeting fkbp5 (C), fkbp7 (D) or scrambled gRNA at the one-cell stage. They were raised in E3 solution to 3 dpf and transferred to the control (Control) or induction medium (induced). NaR cells were quantified 2 days later. Data shown are mean ± SD. n = 17 ~ 69.

Acknowledgments

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