FIGURE

FIGURE 6

ID

ZDB-FIG-231130-57

Publication

Belmonte-Mateos et al., 2023 - Hindbrain rhombomere centers harbor a heterogenous population of dividing progenitors which rely on Notch signaling

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FIGURE 6

Progenitor cells in the rhombomere centers are Notch-responsive. Wild-type embryos were treated with either DMSO (A–E, K–L) or the gamma-secretase inhibitor LY411575 (F–J, M,N) for 6 h at 36 hpf (A–J) or at 48 hpf (K–N). Embryos were in situ hybridized with fabp7a(A,F,K,M), slc1a2a(B,G), neuroD4(C,H), and hey1(E,J), or immunostained with Sox2 and HuC (D,I,L,N). Dorsal MIP with anterior to the top. White arrowheads indicate the rhombomere boundaries. Numbers at the bottom indicate the individuals with the displayed phenotype over the total of analyzed specimens. Scale bar, 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol