FIGURE

Figure 1

ID

ZDB-FIG-231002-25

Publication

van Alen et al., 2023 - Mycobacterium tuberculosis β-lactamase variant reduces sensitivity to ampicillin/avibactam in a zebrafish-Mycobacterium marinum model of tuberculosis

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Figure 1

Expression of Mtb blaC in Mmar. (a) Amplification of blaC and housekeeping genes sigA and rrs during one-step RT-qPCR using RNA isolated from Mmar expressing wild-type Mtb blaC as template. (b) Relative expression of blaC variants as determined by RT-qPCR. Data represent three biological replicates, each with two technical replicates, and the blaC transcripts were normalized to sigA. The error bars represent one standard deviation. One-way ANOVA with Dunnett’s multiple comparison test indicates a significant difference between blaC WT and blaC D172N (p < 0.05).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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