Fig. 4.

Loss of Notch1a but not Emx2 impacts cell-pair rotations. (A) Handedness of cell-pair inversions in wild-type, emx2 and notch1a mutant larvae. (B) Comparison of the onset (duration of Phase 1) of inverting cell pairs from wild type, emx2 and notch1a mutants. (C) Comparison of the rotation duration (Phase 2) of inverting cell-pairs from wild-type, emx2 mutant and notch1a mutant larvae. (D) Comparison of the termination time (Start of Phase 3) of inverting cell pairs from wild-type, emx2 mutant and notch1a mutant larvae. (A-D) n (number of cell pairs)=40 from wild-type, 23 from emx2 mutant, 9 from notch1a mutant larvae. Statistics were calculated using an unpaired two-sided Student's t-test. Box plots show median values (middle bars) and first (Q1) to third (Q3) interquartile ranges (boxes); upper whisker is either 1.5× the interquartile range or the maximum value (whichever is the smallest) and lower whisker is either 1.5× the interquartile range or the minimum value (whichever is the biggest). Each point represents the cells during a rotation.