FIGURE

Figure 5

ID
ZDB-FIG-230416-93
Publication
Rolland et al., 2023 - Prolonged Piezo1 Activation Induces Cardiac Arrhythmia
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Figure 5

Optical mapping recordings of Yoda1-treated larvae. (A) Traces of optical action potentials recorded in the ventricular region of the larvae’s hearts, in control (DMSO) or after prolonged exposure to Yoda (50 µM). Arrows indicated prolonged ventricular depolarization. (B) Heart rate (ventricular action potentials per minute) and (C) coefficient of variability of the action potential interval in control (DMSO) and after prolonged exposure to Yoda 50 µM (n = 19 and 23, respectively). *: p < 0.05 and ***: p < 0.001 by unpaired t-test.

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