Fig. 2
- ID
- ZDB-FIG-230302-15
- Publication
- Kamstra et al., 2022 - Leptin regulates glucose homeostasis via the canonical Wnt pathway in the zebrafish
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Regulation of glucose homeostasis and body weight in adult zebrafish. (A) Glucose tolerance in normal-fed lepanz301 fish, lepbnz302 fish, leprnz303 fish, and wild-type controls (n = 12). (B) Baseline blood glucose levels of normal-fed and overfed lepanz301 fish, lepbnz302 fish, leprnz303 fish, and wild-type controls. ****p < .0001, two-way ANOVA. (C) Glucose tolerance in overfed lepanz301 fish, lepbnz302 fish, leprnz303 fish, and wild-type controls (n = 12). (D) Area under the curve of (A) and (C). *p < .05, one-way ANOVA; #p < .05, two-way ANOVA. (E) Body weights of lepanz301 fish, lepbnz302 fish, leprnz303 fish, and wild-type control on a 6-week normal diet or overfeeding regime. ***p < .001, repeated-measures ANOVA. (F) Standard length of normal-fed and overfed lepanz301 fish, lepbnz302 fish, leprnz303 fish, and wild-type controls at 0, 3, and 6 weeks. *p < .05, one-way ANOVA. (G–J) Examples of leptin receptor-deficient and wild-type zebrafish at the start and end of the overfeeding regime |
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Stage: | Adult |