FIGURE

Figure 2

ID

ZDB-FIG-230217-114

Publication

Hanot et al., 2023 - The Contribution of the Zebrafish Model to the Understanding of Polycomb Repression in Vertebrates

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Figure 2

Deposition of the Polycomb-associated histone marks. Targeting of the PRC2 complex through the action of auxiliary proteins (white circles) leads to methylation at H3K27 (purple dashed arrow). This post-translational modification is recognized by the CBX subunit (blue) of the cPRC1 complex, which in turn ubiquitinylates H2AK119 (black dashed arrow). The ncPRC1 complexes containing RYBP/YAF2 (green) are recruited to chromatin, irrespective of H3K27me3, by the means of auxiliary subunits (blue arrow). Within all PRC complexes, some auxiliary proteins are involved in the stimulation of the catalytic activity (red arrows).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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