FIGURE

Figure 6

ID
ZDB-FIG-221226-7
Publication
Linnerz et al., 2022 - Uricase-Deficient Larval Zebrafish with Elevated Urate Levels Demonstrate Suppressed Acute Inflammatory Response to Monosodium Urate Crystals and Prolonged Crystal Persistence
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Figure 6

MSU crystal aggregates within uricase-deficient larvae are dominated by macrophages. (A) Live confocal imaging of MSU crystals within Tg(mfap4:mCherry);uox−/− larvae at 4 days post injection (dpi). Insets, magnified views of boxed regions showing MSU crystal-laden macrophages. (B) Live confocal imaging of MSU crystals within Tg(mfap4:EGFP);(mpx:NTRmCherry);uox−/− larvae at 4 dpi. Inset, magnified view of boxed region showing red fluorescent neutrophil debris. Scale bars: 100 µm in (A), 50 µm in (B).
Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Observed In:
Stage Range: Long-pec to Day 6

Phenotype Detail
Acknowledgments
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