FIGURE

Fig. 11

ID

ZDB-FIG-220912-153

Publication

McCarthy et al., 2022 - Prolonged Hyperglycemia Causes Visual and Cognitive Deficits in Danio rerio

Other Figures

All Figure Page

Back to All Figure Page

Fig. 11

Overview of cognitive and visual performance. For each experiment: 8 wk Full = 8 weeks of hyperglycemia; 8 wk WO = 8-week washout experiment with fish exposed to glucose for 4-weeks followed by a 4-week recovery period; 12 wk Full = 12 weeks of hyperglycemia; 12 wk WO = 12-week washout experiment with fish exposed to glucose for 8-weeks followed by a 4-week recover period. Here we can see that water-treated fish displayed learning in over 50% of the analyses (denoted by the arrow), whereas mannitol displayed learning in exactly 50% of the analyses. Glucose-treated fish displayed learning in 0% of the analyses with two exceptions. At 8 wk washout denoted by the single asterisk, glucose-treated fish showed evidence of slight learning although they did not pass the threshold, and at 12-weeks full denoted by the double asterisk glucose-treated fish showed evidence of memory, but no new learning.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.