FIGURE

Fig. 2

ID
ZDB-FIG-220905-8
Publication
Lin et al., 2022 - Biallelic variants in WARS1 cause a highly variable neurodevelopmental syndrome and implicate a critical exon for normal auditory function
Other Figures
All Figure Page
Back to All Figure Page
Fig. 2

Defect in mitosis cell division in Caenorhabditis elegans germline upon WARS-1 depletion. (a) Schematic representation of hermaphrodite germline. (b) DAPI staining of the isolated germline of the control and wars-1 RNAi. The dashed box indicates the mitotically active region of the germline. (c) Zoom-in of the mitotic zone of control and wars-1 RNAi (d) Knocking down wars-1 using RNAi results in a reduction in the number of mitotic cells compared to the control. (n = 6, ****p < .0001). DAPI, 4′,6-diamidino-2-phenylindole; RNAi, RNA interference.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Hum. Mutat.