FIGURE

Fig. 1

ID

ZDB-FIG-220719-17

Publication

Morales Fénero et al., 2021 - Short chain fatty acids (SCFAs) improves TNBS-induced colitis in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

SCFAs increase survival in TNBS-exposed larvae. A. Experimental design of SCFAs and TNBS treatment. Larvae were treated with SCFAs from 3 to 10 dpf with a change of medium at day 7. TNBS was added to the medium at 7 dpf and kept until 10 dpf. B. Percent survival of larvae exposed to SCFAs at 3 mM (SCFA3), 6 mM (SCFA6) and 9 mM (SCFA9), from 3 to 10 dpf. Log-rank (Mantel-Cox), ****p < 0.0001 compared to control. N = 90–130. C. Percent survival of larvae exposed to TNBS 50 μg/mL (T50) from 7 to 10 dpf and treated with SCFA 3, 6 and 9 mM from 3 to 10 dpf. Log-rank (Mantel-Cox), ****p < 0.0001 compared to control. N = 100–136. D. Percent survival of larvae exposed to TNBS 50 μg/mL (T50), 75 μg/mL (T75) and 100 μg/mL (T100) from 7 to 10 dpf and treated with SCFA 3 mM from 3 to 10 dpf. Log-rank (Mantel-Cox), ****p < 0.0001 compared to control. N = 70–80.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Conditions:	chemical treatment by environment: 2,4,6-trinitrobenzenesulfonic acid chemical treatment by environment: short-chain fatty acid
Observed In:	whole organism
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Curr Res Immunol