FIGURE

Fig. 3

ID

ZDB-FIG-220603-23

Publication

Tanaka et al., 2022 - Chemogenetic Depletion of Hypophysiotropic GnRH Neurons Does Not Affect Fertility in Mature Female Zebrafish

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Fig. 3

GnRH3 neuron-ablated females exhibit normal fertility. (A) Number of fertilized eggs per spawn (fecundity), percentage of fertilized eggs (fertility), and hatching rate from the experimental females paired with WT males before treatment, and at 28 days of treatment. (B) Gonadosomatic index (GSI) (n = 7–11). (C) Representative ovarian sections stained with hematoxylin and eosin. Scale bars, 500 µm. Bottom panels, images of the intact ovaries with the corresponding GSI (mean ± SEM) adjacent to each image. Scale bars, 1 mm. WT-Mtz, WT siblings treated with 2 mM metronidazole (Mtz); Tg-Cont, Tg(gnrh3:Gal4ff; UAS:nfsb-mCherry) treated with vehicle; Tg-Mtz, Tg(gnrh3:Gal4ff; UAS:nfsb-mCherry) treated with 2 mM Mtz. p > 0.05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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