FIGURE

Fig. 4

ID

ZDB-FIG-220509-14

Publication

Amanda et al., 2022 - IRF4 drives clonal evolution and lineage choice in a zebrafish model of T-cell lymphoma

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Fig. 4

IRF4-driven tumor cells possess malignant features.

A Representative microscopy images of three recipient fish at 1, 2, 3, and 4 weeks after the first transplantation. Panels show merged fluorescence and brightfield images. Scale bar = 4 mm. B Table showing the engraftment rate of five independent donor tumor fish. C Gene expression pattern of the tcr-γ variable regions in eight representative samples. The cells in the UMAP plot are colored by the marker gene expression level. D Pie charts showing the percentage of mono-, oligo-, and polyclonal tumors analyzed by qRT-PCR in three different genotype settings. Source data are provided as a Source Data file.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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