FIGURE

Fig. 1.

ID

ZDB-FIG-220305-15

Publication

Baronio et al., 2021 - Abnormal brain development of monoamine oxidase mutant zebrafish and impaired social interaction of heterozygous fish

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Fig. 1.

Behavioral phenotype of mao mutants. (A) mao^−/− larvae were hypoactive during diurnal and nocturnal (gray shaded area) locomotor activity tracking at 6 dpf. n=16 for mao^+/+, n=16 for mao^+/− and n=15 for mao^−/−. (B) Larvae at 6 dpf were exposed to alternating 2 min periods of light and darkness (gray shaded areas), with three periods of darkness in total. n=15 mao^+/+ and n=16 for mao^+/− and mao^−/−. (C-E) Analysis of the larval response to sudden darkness [first (C), second (D) and third (E) flash response] in 1 s bins. Gray shaded areas indicate periods of darkness. (F) Mean values for maximum velocity during ten acoustic/vibrational stimuli with a 20 s interstimulus interval (ISI). n=15 for mao^+/+, n=16 for mao^+/− and n=12 for mao^−/−. Two-way ANOVA followed by Tukey's post hoc test was used for statistical analysis. ^#P<0.05 (mao^+/− versus mao^+/+ and mao^−/−), *P<0.05 (mao^+/+ and mao^+/− versus mao^−/−), ^§P<0.05 (mao^+/+ versus mao^−/−), ^€P<0.05 (mao^+/− versus mao^−/−), ^‡P<0.05 (mao^+/− versus mao^+/+).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mao^{sa31732/sa31732} mao^sa31732/+
Conditions:	altered light dark cycle lighting conditions vibration
Observed In:	startle response swimming behavior
Stage:	Day 6

Phenotype Detail

Acknowledgments

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