FIGURE

Fig. 3

ID

ZDB-FIG-220131-273

Publication

Ziegler et al., 2021 - Mandipropamid as a chemical inducer of proximity for in vivo applications

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Fig. 3

Protein translocation in living zebrafish embryos.

a, Schematic illustration of workflow for in vivo application in zebrafish embryos. Fertilized eggs were injected with vectors for LYN–mCherry–PYR^Mandi or TOM20–mCherry–PYR^Mandi and eGFP–ABI expression, resulting in mosaic expression of target proteins at 3–5 dpf. b–d, Confocal microscopy images of different cell types (fin cells (b), epithelial cells (c) and muscle cells (d)) in living zebrafish embryos expressing receiver and plasma membrane-localized receptor domains before and 10–20 min after addition of 500 nM Mandi are shown. Data are representative of ≥three independent experiments for each cell type; scale bar, 40 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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