FIGURE

Fig 1

ID

ZDB-FIG-211122-23

Publication

Kikel-Coury et al., 2021 - Identification of astroglia-like cardiac nexus glia that are critical regulators of cardiac development and function

Other Figures

All Figure Page

Back to All Figure Page

Fig 1

Adult gfap⁺ cells are conserved across species.

(A) Confocal maximum z-projection from adult zebrafish, mouse, and human ventricle stained with GFAP. Schematics of hearts per species (above) indicate location of imaging. Gfap⁺ cells are present across species. (B) Confocal 10 μm z-projection of adult Tg(gfap:gfp) ventricles with 3 distinct morphologies of gfap⁺ cells. (C) Quantification of process length between gfap⁺ cell types. (D) Quantification of process number per gfap⁺ cell type. (E) Confocal maximum z-projection from adult Tg(myl7:gfp) ventricles stained with AcTub and GFAP showing localization. Gfap⁺ cells localize with AcTub⁺ axons. Data are represented as mean ± SEM. Scale bar equals 10 μm. Statistics summarized in S1 Table. See S1 Data for raw data. A, atrium; AcTub, acetylated tubulin; AO, aorta; BA, bulbous arteriosus; LA, left atrium; LV, left ventricle; PA, pulmonary artery; RA, right atrium; RV, right ventricle; SV, sinoatrial valve; V, ventricle.

Expression Data

Genes:	Cerulean GFP
Antibodies:	Ab1-tuba Ab2-gfap
Fish:	co19Tg mi2001Tg
Anatomical Terms:	cardiac conduction system axon cardiac ventricle glial cell (sensu Vertebrata) ventricular myocardium
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Biol.