FIGURE

Fig 3

ID

ZDB-FIG-210823-7

Publication

Waldmann et al., 2021 - The broad role of Nkx3.2 in the development of the zebrafish axial skeleton

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Fig 3

Sagittal sections of wild-type 14 dpf (A, A’), 30 dpf (C, C’) and 90 dpf (E, E’) and nkx3.2 mutant 14 dpf (B, B’) 30 dpf (D, D’) and 90 dpf (F, F’) zebrafish stained with Nuclear Red. (A, A’, C, C’, E, E’) Stained histology sections displaying a normal jaw joint development between Meckel’s cartilage (m) and palatoquadrate (pq), respectively articular (art) and quadrate (q) in wild-type fish. (B, B’, D, D’, F, F’) nkx3.2 mutants do not display a jaw joint. Chondrocyte maturation and ossification seem not to be affected in nkx3.2^{uu2803/uu2803} besides the absence of joint-typical cells lining the articulating elements. Dashed box in (A-F) marks the magnified region in (A’-F’). Asterisk marks the fused element. m–Meckel’s cartilage, pq–palatoquadrate, art–articular, q–quadrate. Scale bars: 200μm (A-F), 100μm (A’-F’).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	nkx3-2^{uu2803/uu2803}; ba2Tg (AB)
Observed In:	mandibular arch skeleton chondrocyte development mandibular arch skeleton ossification Meckel's cartilage-palatoquadrate cartilage joint Meckel's cartilage-palatoquadrate cartilage joint chondrocyte
Stage Range:	Days 14-20 to Adult

Phenotype Detail

Acknowledgments

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