Figure 4 - figure supplement 2

Klf2a expression is regulated by ccm2 expression and by blood flow.

(A and A’) A ccm2 morphant displayed an increase of endothelial nuclear EGFP KLF2a reporter expression, whereas a tnnt morphant displayed a decrease of endothelial nuclear EGFP KLF2a reporter expression compared with a control morpholino-injected embryo (C and C’). EGFP expression was driven by klf2a promoter in Tg(klf2a:H2b-EGFP), and endothelial cells were labeled by mcherry in Tg(kdrl:mcherry). Arrows indicated the endothelial cell nucleus. Scale bar: 50 µm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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