Figure 1 - figure supplement 2

Approximately 10% of <italic toggle='yes'>ccm2</italic> CRISPR zebrafish embryos exhibited dilation of heart and increased branch points of subintestinal vein.

Microinjection was performed on Tg(fli1:EGFP) embryos. (A and B) Both atrium and ventricle were dilated in ~10% of ccm2 CRISPR embryos on 2 days post fertilization (dpf) (A) compared with normal heart in control (B). The heart was outlined by dash lines. (C and D) Increased branch points were observed on 3 dpf in ~10% of ccm2 CRISPR embryos indicated by arrows. Scale bar: 100 µm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Long-pec to Protruding-mouth

Phenotype Detail
Acknowledgments
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