Figure 5
- ID
- ZDB-FIG-210526-34
- Publication
- Tarashansky et al., 2021 - Mapping single-cell atlases throughout Metazoa unravels cell type evolution
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(A) Schematic illustrating edge (left) and node (right) transitivities, defined as the fraction of triads (set of three connected nodes) in closed triangles. (B) The percentage of cell type pairs that are topologically equivalent to the green edge in each illustrated motif. (C) Network graphs showing highly connected cell type families. Each node represents a cell type, color-coded by species (detailed annotations are provided in Supplementary file 7). Mapped cell types are connected with an edge. (D) Boxplot showing the median and interquartile ranges of node transitivities for highly connected cell type groups. For all box plots, the whiskers denote the maximum and minimum observations. The average node transitivity per group is compared to a bootstrapped null transitivity distribution, generated by repeatedly sampling subsets of nodes in the cell type graph and calculating their transitivities. **p<5×10−5, ***p<5×10−7. (E) Boxplot showing the median and interquartile ranges of the number of enriched gene pairs in highly connected cell type groups. All cell type connections in these groups have at least 40 enriched gene pairs (dashed line). |