FIGURE

Fig. 10

ID

ZDB-FIG-210512-92

Publication

Prajsnar et al., 2020 - The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils

Other Figures

All Figure Page

Back to All Figure Page

Fig. 10

Proposed model of fate of S. aureus within neutrophils. Staphylococci are internalized by neutrophils and trapped within LC3-associated phagosomes (LAPosomes) triggered by NADPH oxidase. LAPosomes do not get acidified and provide a replication niche for internalized S. aureus, which eventually will damage the phagosomal membrane and escape into the cytoplasm. This is sensed by Sqstm1/p62 – a member of the selective autophagy machinery, which could lead to the formation of autophagosomes containing staphylococci and leading to pathogen inactivation

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Autophagy