Figure 2
- ID
- ZDB-FIG-210503-14
- Publication
- Kamel et al., 2021 - A Heterozygous Mutation in Cardiac Troponin T Promotes Ca2+ Dysregulation and Adult Cardiomyopathy in Zebrafish
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Morphological changes in tnnt2a+/RK94del observed during different stages of development. (A,B) Images of 5 dpf embryonic hearts for tnnt2a+/+ and tnnt2a+/RK94del. (C–H) H&E staining of heart sections of tnnt2a+/+ and tnnt2a+/RK94del at (C,D) 2 weeks post-fertilization, (E,F) 4 weeks post-fertilization, and (G,H) 7 weeks post-fertilization. (I–L) In situ hybridization on adult heart sections of tnnt2a+/+a nd tnnt2a+/RK94del stained for (I,J) amhc, a marker of atrial cells, and (K,L) vmhcl, a marker for adult zebrafish ventricular cells. Images were taken at a magnification of 20×. Scale bars are 100 µm (A–F), 50 µm (G–I), and 200 µm for whole-heart tile scans (I–L) with 50 µm for zoom-in regions. A: atrium, V: ventricle, BA: bulbus arteriosus. |
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Stage: | Adult |
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Stage Range: | Day 5 to Adult |