FIGURE

Figure 6

ID

ZDB-FIG-210414-70

Publication

Ambrosini et al., 2020 - Progressively De-Differentiated Pancreatic Cancer Cells Shift from Glycolysis to Oxidative Metabolism and Gain a Quiescent Stem State

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Figure 6

Metabolic features of adherent cells derived by CSCs. Metabolomic quantification of intracellular levels of metabolites reported as fold change relative to parental cells. Metabolites from glycolysis (A), pentose phosphate pathway (B), and tricarboxylic acid cycle (C) in Panc1 P cells and adherent cells derived from Panc1 CSCs after 2 months of culture in DM. Legend: P cells: parental cells; AdCSCs: adherent cells derived from the indicated CSCs cultured in DM for more than 2 months. Values are the means (± SE) of three technical replicates and two independent biological replicates. Statistical legend: p < 0.05 (*) P cells versus AdCSCs; (§) AdCSCs 2 weeks versus AdCSCs 4 weeks; (#) AdCSCs 4 weeks versus AdCSCs 8 weeks.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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