FIGURE
Fig. 3
- ID
- ZDB-FIG-210322-21
- Publication
- Leijten et al., 2021 - Thermal Proteome Profiling in Zebrafish Reveals Effects of Napabucasin on Retinoic Acid Metabolism
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Fig. 3
TPP indicates differential effects of napabucasin treatment on selected proteins. Stat33 (A) does not show any shift, whereas Stat5 (B) shows a small shift. However, a shift was detected in Aldh1a2 (C) and Aldh1a3 (D). The known interactor of napabucasin Nqo1 (E) shows no shift. Interestingly, another known interactor, Pora, (F) shows a shift indicating destabilization. Data points (n = 2 independent experiments) are shown as mean ± SEM, melting curve fitting was performed according to chemical denaturation theory. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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