FIGURE

Fig 4

ID

ZDB-FIG-210313-4

Publication

Cabrera-Quio et al., 2021 - Zebrafish Ski7 tunes RNA levels during the oocyte-to-embryo transition

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Fig 4

Genes overexpressed in the <italic>ski7</italic> mutants are lowly expressed.

(A) Genes up-regulated in the absence of Ski7 show low expression levels in wild type. Expression levels of DEGs in wild type for every stage of the time course, as measured by transcripts per million (TPM). * indicates p-value < 0.01 from Wilcoxon test in comparison to unchanged genes. (B) Metagene profiles of up-regulated (top), down-regulated (middle), and unchanged genes (bottom) of wild type and ski7^-/- mutants at a representative stage for each period during the oocyte-to-embryo transition (oogenesis = O4, mature eggs = activated eggs, embryogenesis = E1). WT, gray; ski7^-/-, purple. (C) Up-regulated genes have higher read density towards their 3’ end. Ratio of read density of ski7^-/-/WT per gene body region (5’ UTR, CDS, 3’ UTR) for all stages covered in this study. * p-value < 0.05; Wilcoxon test of read density of ski7^-/- vs. read density of WT per region.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hbs1l^vbc10/vbc10
Observed In:	nuclear-transcribed mRNA catabolic process
Stage:	1-cell

Phenotype Detail

Acknowledgments

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