FIGURE

Figure 2—figure supplement 2.

ID

ZDB-FIG-210208-102

Publication

Dilshat et al., 2021 - MITF reprograms the extracellular matrix and focal adhesion in melanoma

Other Figures

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Figure 2—figure supplement 2.

MITF directly regulates NGFR and MLANA expression.

(a, b) Gene expression of NGFR and MLANA measured by RT-qPCR in EV-SkMel28, ∆MITF-X2, and ∆MITF-X6 cell lines. Expression was normalized to EV-SkMel28 cells. Error bars represent standard error of the mean, * p value <0.05 was calculated by one-way ANOVA (multiple correction with Dunnett test). (c, d) IGV genome browser showing MITF ChIP-seq tracks from MITF CUT and RUN in SkMEL28 (rep1 and rep2), MITF ChIP-seq in COLO829 cells (Webster et al., 2014), and HA-MITF ChIP-seq in 501Mel (Laurette et al., 2015) in NGFR and MLANA.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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