FIGURE

Fig 11

ID

ZDB-FIG-200718-38

Publication

Deveau et al., 2020 - Thyroid hormone receptor beta mutations alter photoreceptor development and function in Danio rerio (zebrafish)

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Fig 11

Optomotor response test using a black/white stimulus.

Controls use a drifting black and white grating pattern with wild types (+/+) (N = 18 larvae), 6BP+1 heterozygotes (+/-) (N = 12 larvae), and 6BP+1 mutants (-/-) (N = 23 larvae) at 7 dpf. Colored markings in the dishes represent larval zebrafish locations before and after the one-minute stimulus. The arrows indicate the direction of the stimulus. (A, B, C) Wild types, heterozygotes, and mutants respectively start scattered in the dish. (A’, B’, C’) Each genotype moved with the stimulus showing significant pooling of larvae at the bottom edge. Experiment was repeated 2 times per genotype, with similar outcomes for each trial. Significance, given by the Fisher Exact Test, refers to the combined numbers from the two plates (Table 2).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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